Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | TDO2 | P48775 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808164 | 0.85 | IDO1 (0.43) | IDO1TDO2GAAOPRM1OPRD1 | |
| SCHEMBL7522383 | 0.79 | IDO1 (0.50) | IDO1TDO2GAAOPRM1OPRD1 | |
| SCHEMBL41457 | 0.78 | IDO1 (0.53) | IDO1TDO2GAAOPRM1OPRD1 | |
| SCHEMBL3782815 | 0.76 | IDO1 (0.52) | IDO1TDO2GAAOPRM1OPRD1 | |
| SCHEMBL17071857 | 0.74 | IDO1 (0.50) | IDO1TDO2GAAOPRM1OPRD1 | |
| SCHEMBL17071859 | 0.74 | IDO1 (0.50) | IDO1TDO2GAAOPRM1OPRD1 | |
| SCHEMBL3999911 | 0.74 | IDO1 (0.55) | IDO1TDO2GAAOPRM1OPRD1 | |
| SCHEMBL8108090 | 0.74 | IDO1 (0.50) | IDO1TDO2GAAOPRM1OPRD1 | |
| SCHEMBL11601662 | 0.74 | IDO1 (0.50) | IDO1TDO2GAAOPRM1OPRD1 | |
| SCHEMBL16154382 | 0.74 | IDO1 (0.50) | IDO1TDO2GAAOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200417-A | Administering to inhibait gastric acid secretion in mammals | SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) | 1993-04-06 | — | — | US | claimed |