Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680121 | 1.00 | ATM (0.43) | ATMNFE2L2CES1CES2CA12 | |
| SCHEMBL11879384 | 0.87 | MAPT (0.52) | MAPTSMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL11879398 | 0.87 | MAPT (0.52) | MAPTSMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL95443 | 0.81 | CYP3A4 (0.43) | ATMNFE2L2CES1CES2CA12 | |
| SCHEMBL3962527 | 0.81 | ATM (0.45) | ATMCES1CES2MTNR1AMTNR1B | |
| SCHEMBL3962524 | 0.81 | ATM (0.45) | ATMCES1CES2MTNR1AMTNR1B | |
| SCHEMBL4115472 | 0.81 | CYP3A4 (0.43) | ATMNFE2L2CES1CES2CA12 | |
| SCHEMBL1226475 | 0.80 | MTNR1A (0.52) | ATMCES1CES2MTNR1AMTNR1B | |
| SCHEMBL2089770 | 0.79 | PTGS1 (0.43) | ATMCES1CES2MAPTKDM4E | |
| SCHEMBL14457632 | 0.79 | PTGS1 (0.43) | ATMCES1CES2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016120890-A1 | AN ENANTIOSELECTIVE PROCESS FOR THE SYNTHESIS OF (2S,4R)-4-HYDROXYPIPECOLIC ACID | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-08-04 | — | — | WO | claimed |
| CN-107207421-B | Novel trifluoromethylpropionamide derivatives | 豪夫迈·罗氏有限公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-106471405-B | Optical resin composition and film | 株式会社钟化 | 2019-05-03 | — | — | CN | disclosed |
| CN-102939550-B | Phase retardation film and the image display device possessing this phase retardation film | 株式会社日本触媒 | 2016-11-23 | — | — | CN | disclosed |
| WO-2016120890-A1 | AN ENANTIOSELECTIVE PROCESS FOR THE SYNTHESIS OF (2S,4R)-4-HYDROXYPIPECOLIC ACID | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-08-04 | — | — | WO | disclosed |
| EP-3022199-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2016-05-25 | — | — | EP | disclosed |
| CN-105503699-A | Oxo carbon-based compounds, a resin composition comprising the same and a filter containing the resin composition | NIPPON CATALYTIC CHEM IND | 2016-04-20 | — | — | CN | disclosed |
| CN-103313838-B | Method for producing long polymer film, lambda/4 plate, polarizing plate, and liquid crystal display device | KONICA MINOLTA,INC. (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-105074517-A | Optical film and method for fabrication of same, and polarizing plate, liquid-crystal display device, and polarizing projector screen provided with optical film | JX NIPPON OIL & ENERGY CORP | 2015-11-18 | — | — | CN | disclosed |
| CN-105009190-A | Image display device | NITTO DENKO CORP | 2015-10-28 | — | — | CN | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |
| US-6979710-B2 | Curable fluoropolyether rubber compositions and rubber articles | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-12-27 | — | — | US | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-20050043480-A1 | Curable fluoropolyether rubber compositions and rubber articles | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| EP-1422260-A2 | Curable fluoropolyether rubber compositions and rubber articles | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-20040096667-A1 | Curable fluoropolyether rubber compositions and rubber articles | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-05-20 | — | — | US | disclosed |
| EP-1389632-A1 | Curable fluoropolyether rubber compositions and rubber articles | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | ATM 3644/4885NFE2L2 846/4885CES1 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.