Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27770501 | 0.84 | TAAR1 (0.62) | TAAR1HDAC1HDAC8CNR1KDM4E | |
| SCHEMBL28945212 | 0.82 | TAAR1 (0.66) | TAAR1HDAC1HDAC8CNR1KDM4E | |
| SCHEMBL3920885 | 0.82 | TAAR1 (0.61) | TAAR1CNR1KDM4EMEN1KMT2A | |
| SCHEMBL46769 | 0.81 | MLYCD (0.55) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL19403914 | 0.81 | CNR1 (0.71) | TAAR1HDAC1HDAC8CNR1KDM4E | |
| Hydrochloric Acid SCHEMBL11525399 | 0.81 | TAAR1 (0.64) | TAAR1HDAC1HDAC8CNR1KDM4E | |
| Hydrochloric Acid SCHEMBL31173764 | 0.81 | TAAR1 (0.59) | TAAR1CNR1KDM4EMEN1KMT2A | |
| SCHEMBL4536310 | 0.80 | CNR1 (0.62) | TAAR1HDAC1HDAC8CNR1KDM4E | |
| Hydrochloric Acid SCHEMBL8701788 | 0.80 | IDO1 (0.54) | TAAR1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL3119866 | 0.79 | TAAR1 (0.67) | TAAR1HDAC1HDAC8CNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236951-A | Administering a phenylethanolamine derivative | SANOFI (FR) | 1993-08-17 | — | — | US | claimed |