Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 3/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.54 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
| ▸ | IL2 | P60568 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9482204 | 1.00 | ACHE (0.56) | ACHECA12CA9CA1CA2 | |
| SCHEMBL5597588 | 0.85 | ACHE (0.70) | ACHECA12CA9CA1SNCA | |
| SCHEMBL29360789 | 0.85 | ACHE (0.70) | ACHECA12CA9CA1SNCA | |
| SCHEMBL3353611 | 0.85 | ACHE (0.70) | ACHECA12CA9CA1SNCA | |
| Tachioside SCHEMBL13577078 | 0.83 | POLB (0.63) | ACHECA12CA9CA1TYR | |
| Tachioside SCHEMBL9576060 | 0.83 | POLB (0.63) | ACHECA12CA9CA1TYR | |
| Tachioside SCHEMBL13576891 | 0.83 | POLB (0.63) | ACHECA12CA9CA1TYR | |
| Tachioside SCHEMBL14884668 | 0.83 | POLB (0.63) | ACHECA12CA9CA1TYR | |
| SCHEMBL28414974 | 0.83 | CA12 (0.53) | CA12CA9CA1CA2TYR | |
| SCHEMBL988823 | 0.81 | TYR (0.59) | TYRSLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221606-A | REAGENT AND KIT FOR ENZYME ASSAY COMPRISING A SUBSTRATE CONSONANT WITH GIVEN ENZYME TO BE ASSAYED | KING'S COLLEGE LONDON (GB) | 1993-06-22 | — | — | US | disclosed |
| EP-0375723-A1 | SUBSTRATES FOR THE ASSAY OF ENZYMES. | KING S COLLEGE LONDON (GB) | 1990-07-04 | — | — | EP | disclosed |
| WO-1989002473-A1 | SUBSTRATES FOR THE ASSAY OF ENZYMES | KING'S COLLEGE LONDON (GB) | 1989-03-23 | — | — | WO | disclosed |