Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL948238 | 1.00 | GPR119 (0.47) | GPR119STSKDM4EPKMMEN1 | |
| SCHEMBL950602 | 0.83 | GPR119 (0.44) | GPR119STSKDM4EPKMMEN1 | |
| SCHEMBL950601 | 0.83 | GPR119 (0.44) | GPR119STSKDM4EPKMMEN1 | |
| SCHEMBL20015325 | 0.82 | GPR119 (0.60) | GPR119KDM4EPKMMEN1KMT2A | |
| SCHEMBL948590 | 0.80 | GPR119 (0.45) | GPR119STSKDM4EPKMMEN1 | |
| SCHEMBL948589 | 0.80 | GPR119 (0.45) | GPR119STSKDM4EPKMMEN1 | |
| SCHEMBL20015682 | 0.79 | GPR119 (0.57) | GPR119STSKDM4EPKMMEN1 | |
| SCHEMBL20015272 | 0.79 | GPR119 (0.57) | GPR119STSKDM4EPKMMEN1 | |
| SCHEMBL947677 | 0.79 | KDM4E (0.49) | GPR119STSKDM4EPKMHPGDS | |
| SCHEMBL14433203 | 0.78 | GPR119 (0.46) | GPR119STSKDM4EPKMHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1564213-A1 | IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | HRH4, F2, HRH2 | GPR119 1327/4885STS 69/4885KDM4E 1356/4885 |
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | F2, H1-3, CYC1 | GPR119 1118/4885STS 62/4885KDM4E 1558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.