Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | FNTA | P49354 | 4/20 | 0.41 |
| ▸ | FNTB | P49356 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483614 | 1.00 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL13322789 | 0.84 | KDM4E (0.44) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL19934736 | 0.82 | BMP1 (0.41) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL19934769 | 0.82 | BMP1 (0.41) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL13402975 | 0.82 | KDM4E (0.38) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4986510 | 0.82 | KDM4E (0.55) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL22117302 | 0.81 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL22117303 | 0.81 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL23154372 | 0.81 | KDM4E (0.37) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL23154107 | 0.81 | KDM4E (0.37) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128831-B1 | DRUG ADMINISTRATION | Carey, Martin C. (US) | 1993-01-07 | — | — | EP | claimed |
| US-4746508-A | USING A BIOCOMPATIBLE STEROID FOR ENHANCED DRUG DELIVERY | BETH ISRAEL HOSPITAL ASSN. (US) | 1988-05-24 | — | — | US | claimed |
| US-4548922-A | STEROID INCREASESPERMEABILITY OF SURFACE TO DRUG | BETH ISRAEL HOSPITAL (US) | 1985-10-22 | — | — | US | claimed |
| EP-0128831-A2 | Drug administration | Carey, Martin C. (US) | 1984-12-19 | — | — | EP | claimed |
| EP-0128831-B1 | DRUG ADMINISTRATION | Carey, Martin C. (US) | 1993-01-07 | — | — | EP | disclosed |
| US-5011678-A | Suspension of biocompatible polypeptide drug, steroid and fluorocarbon propellant; for mucosal area; antidiabetic, osteoporosis, Paget*s disease; sodium tauro-24,25-dihydro-fusidate | CALIFORNIA BIOTECHNOLOGY INC. (US) | 1991-04-30 | — | — | US | disclosed |
| US-4959358-A | STEROID WHICH PROMOTES DRUG ABSORPTION ACROSS MUCOUS MEMBRANES | BETH ISRAEL HOSPITAL ASSN. (US) | 1990-09-25 | — | — | US | disclosed |
| WO-1990009167-A1 | COMPOSITION AND METHOD FOR ADMINISTRATION OF PHARMACEUTICALLY ACTIVE SUBSTANCES | CALIFORNIA BIOTECHNOLOGY INC. (US) | 1990-08-23 | — | — | WO | disclosed |
| US-4746508-A | USING A BIOCOMPATIBLE STEROID FOR ENHANCED DRUG DELIVERY | BETH ISRAEL HOSPITAL ASSN. (US) | 1988-05-24 | — | — | US | disclosed |
| US-4548922-A | STEROID INCREASESPERMEABILITY OF SURFACE TO DRUG | BETH ISRAEL HOSPITAL (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0128831-A2 | Drug administration | Carey, Martin C. (US) | 1984-12-19 | — | — | EP | disclosed |