Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1434515 | 0.67 | MAPT (0.34) | KDM4ELMNAMAPTPOLBRAB9A | |
| SCHEMBL912707 | 0.67 | POLB (0.35) | KDM4EMAPTPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL8400813 | 0.62 | POLB (0.36) | POLB | |
| SCHEMBL22996784 | 0.58 | PDE3B (0.46) | KDM4EPDE3BPDE3ALMNAMAPT | |
| SCHEMBL19027031 | 0.58 | MAPT (0.35) | KDM4EADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL19027124 | 0.58 | GAA (0.40) | KDM4EADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL7340553 | 0.57 | GAA (0.37) | KDM4EADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL9339048 | 0.57 | CA12 (0.50) | KDM4EPDE3BPDE3ALMNAMAPT | |
| SCHEMBL2672209 | 0.57 | CA12 (0.50) | KDM4EPDE3BPDE3AADRA2AADRA2B | |
| SCHEMBL12989805 | 0.57 | ALDH1A1 (0.40) | KDM4EPDE3BPDE3ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5241057-A | Blue shades | BAYER AKTIENGESELLSHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| EP-0321784-B1 | FORMAZANE DYES CONTAINING HEAVY METALS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0255890-B1 | PROCESS FOR THE REACTION OF AMINES WITH HETEROCYCLIC REACTIVE COMPOUNDS | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0255890-A1 | Process for the reaction of amines with heterocyclic reactive compounds | BAYER AG (DE) | 1988-02-17 | — | — | EP | disclosed |
| EP-0158882-B1 | TRIPHENEDIOXAZINE DYES | BAYER AG (DE) | 1987-12-16 | — | — | EP | disclosed |
| EP-0144704-B1 | REACTIVE DYES | BAYER AG (DE) | 1987-12-16 | — | — | EP | disclosed |
| US-4659806-A | WASH-AND COLORFASTNESS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| US-4621138-A | Triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-04 | — | — | US | disclosed |
| EP-0189081-A1 | Azo reactive dyes | BAYER AG (DE) | 1986-07-30 | — | — | EP | disclosed |
| EP-0084314-B1 | REACTIVE DISAZO DYES | BAYER AG (DE) | 1986-07-30 | — | — | EP | disclosed |
| EP-0128316-A1 | Reactive disazo dyes | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| EP-0050266-B1 | REACTIVE DISAZO DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING MATERIALS THAT CONTAIN HYDROXYL AND/OR NITROGEN | BAYER AG (DE) | 1984-10-03 | — | — | EP | disclosed |
| EP-0043411-B1 | REACTIVE DISAZO DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING MATERIALS CONTAINING NITROGEN AND/OR HYDROXYLE GROUPS | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |
| EP-0108924-A1 | Heavy metal-containing formazane dyestuffs, methods for their preparation and their use in the dyeing and printing of fibre materials | BAYER AG (DE) | 1984-05-23 | — | — | EP | disclosed |
| EP-0097289-A2 | Azo dyestuffs | BAYER AG (DE) | 1984-01-04 | — | — | EP | disclosed |
| EP-0084314-A2 | Reactive disazo dyes | BAYER AG (DE) | 1983-07-27 | — | — | EP | disclosed |
| EP-0013936-B1 | REACTIVE AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE IN DYEING MATERIALS CONTAINING HYDROXYL GROUPS AND AMIDE GROUPS | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| EP-0021372-B1 | COPPER COMPLEXES OF DISAZO REACTIVE DYESTUFFS | BAYER AG (DE) | 1982-07-07 | — | — | EP | disclosed |
| EP-0050266-A1 | Reactive disazo dyes, process for their preparation and their use in dyeing and printing materials that contain hydroxyl and/or nitrogen | BAYER AG (DE) | 1982-04-28 | — | — | EP | disclosed |
| EP-0043411-A2 | Reactive disazo dyestuffs, process for their preparation and their use in dyeing and printing materials containing nitrogen and/or hydroxyle groups | BAYER AG (DE) | 1982-01-13 | — | — | EP | disclosed |