Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28744460 | 1.00 | CA1 (0.50) | CA1CA4CA2ALDH1A1TDP1 | |
| Acetic Acid SCHEMBL985917 | 0.87 | CA1 (0.38) | CA1 | |
| Acetic Acid SCHEMBL6538192 | 0.80 | FFAR3 (0.50) | ALDH1A1TDP1TSHR | |
| Trifluoroacetic Acid SCHEMBL29830959 | 0.78 | — | — | |
| Acetic Acid SCHEMBL241961 | 0.75 | — | — | |
| SCHEMBL30509232 | 0.75 | — | — | |
| Acetic Acid SCHEMBL3432478 | 0.75 | CA1 (0.89) | CA1CA4CA2ALDH1A1TDP1 | |
| Acetic Acid SCHEMBL3805081 | 0.75 | CA1 (0.89) | CA1CA4CA2ALDH1A1TDP1 | |
| Acetic Acid SCHEMBL711 | 0.75 | — | — | |
| Acetic Acid SCHEMBL29827597 | 0.75 | CA1 (0.89) | CA1CA4CA2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260055268-A1 | HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY AND MELAMINE | PROMERUS, LLC (US) | 2026-02-26 | — | — | US | disclosed |
| US-20250388745-A1 | HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY, MELAMINE AND CLAY | PROMERUS, LLC (US) | 2025-12-25 | — | — | US | disclosed |
| US-20250353943-A1 | FAST PHOTOCURABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL OR 3D PRINTING MATERIALS | PROMERUS, LLC (US) | 2025-11-20 | — | — | US | disclosed |
| EP-4612126-A1 | COMPOSITIONS INCLUDING A MIXTURE OF ISOMERS OF ITACONIMIDE NORBORNENE AND CITRACONIMIDE NORBORNENE | 3M Innovative Properties Company (US) | 2025-09-10 | — | — | EP | disclosed |
| US-12391775-B2 | Fast photocurable polycycloolefin compositions as optical or 3D printing materials | PROMERUS, LLC (US) | 2025-08-19 | — | — | US | disclosed |
| EP-3565850-B1 | POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS | PROMERUS LLC (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-120152955-A | Compositions comprising isomer mixtures of itaconimide norbornene and citraconimide norbornene | 3M创新有限公司 | 2025-06-13 | — | — | CN | disclosed |
| US-20240279251-A1 | Monomer, Polymerizable Composition, and Polymers Derived Therefrom | 3M INNOVATIVE PROPERTIES COMPANY | 2024-08-22 | — | — | US | disclosed |
| WO-2024095078-A1 | COMPOSITIONS INCLUDING A MIXTURE OF ISOMERS OF ITACONIMIDE NORBORNENE AND CITRACONIMIDE NORBORNENE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |
| US-20240002586-A1 | CURABLE COMPOSITIONS, COMPOSITE FOAM, METHOD OF MAKING THE SAME, AND ARTICLE INCLUDING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2024-01-04 | — | — | US | disclosed |
| CN-116490538-A | Curable composition, syntactic foam, method of preparing syntactic foam, and article comprising syntactic foam | 3M创新有限公司 | 2023-07-25 | — | — | CN | disclosed |
| US-20230220132-A1 | FAST PHOTOCURABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL OR 3D PRINTING MATERIALS | PROMERUS, LLC (US) | 2023-07-13 | — | — | US | disclosed |
| US-11639405-B2 | Fast photocurable polycycloolefin compositions as optical or 3D printing materials | PROMERUS, LLC (US) | 2023-05-02 | — | — | US | disclosed |
| WO-2022238774-A1 | MONOMER, POLYMERIZABLE COMPOSITION, AND POLYMERS DERIVED THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-11-17 | — | — | WO | disclosed |
| WO-2022118175-A1 | CURABLE COMPOSITIONS, COMPOSITE FOAM, METHOD OF MAKING THE SAME, AND ARTICLE INCLUDING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-06-09 | — | — | WO | disclosed |
| US-7875686-B2 | comprising 10 to 99 wt. % of norbornene-type cycloolefin monomers; for microelectronic, optoelectronic and micro-optoelectronic applications such as die attach adhesives, underfill materials, prepreg binders, encapsulants | PROMERUS LLC (US) | 2011-01-25 | — | — | US | disclosed |
| EP-1791888-B1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | PROMERUS LLC (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1791888-A1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | Promerus, LLC (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006023511-A1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | PROMERUS LLC (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060041093-A1 | Polycycloolefin polymeric compositions for semiconductor applications | SUMITOMO BAKELITE CO., LTD. (JP) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279251-A1 | Monomer, Polymerizable Composition, and Polymers Derived Therefrom | PBRM1, CARM1, WASF2 | CA1 2484/4885CA4 3150/4885CA2 2415/4885 |
| US-20260055268-A1 | HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY AND MELAMINE | RAD52, PYM1, MCM4 | CA1 1309/4885CA4 1458/4885CA2 2926/4885 |
| US-20250388745-A1 | HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY, MELAMINE AND CLAY | PYM1, MCM4, MELK | CA1 975/4885CA4 1178/4885CA2 2005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.