Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28744460 | 0.87 | CA1 (0.50) | CA1 | |
| Acetic Acid SCHEMBL948383 | 0.87 | CA1 (0.50) | CA1 | |
| Acetic Acid SCHEMBL4653430 | 0.85 | FFAR3 (0.37) | — | |
| Acetic Acid SCHEMBL1469783 | 0.82 | — | — | |
| Acetic Acid SCHEMBL1714983 | 0.82 | — | — | |
| Acetic Acid SCHEMBL28318641 | 0.82 | CA1 (0.57) | CA1 | |
| Acetic Acid SCHEMBL8206910 | 0.76 | — | — | |
| Acetic Acid SCHEMBL17747086 | 0.76 | CA1 (0.57) | CA1 | |
| Acetic Acid SCHEMBL29046887 | 0.76 | CA1 (0.57) | CA1 | |
| Acetic Acid SCHEMBL3173468 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329838-B2 | Norbornene-type polymers, compositions thereof and lithographic processes using such compositions | PROMERUS LLC (US) | 2012-12-11 | — | — | US | claimed |
| US-7799883-B2 | copolymerizing norbornene monomers containing ester groups, sulonamide groups, ethers, alcohols in presence of (Acetonitrile) bis(triisopropylphosphine)palladium(acetate) tetrakis (pentafluorophenyl)borate catalyst and an optional cocatalyst lithium tetrakis(pentafluorophenyl)borate diethyl etherate | PROMERUS LLC (US) | 2010-09-21 | — | — | US | claimed |
| EP-1853972-A2 | NORBORNENE-TYPE POLYMERS, COMPOSITIONS THEREOF AND LITHOGRAPHIC PROCESSES USING SUCH COMPOSITIONS | Promerus LLC (US) | 2007-11-14 | — | — | EP | claimed |
| US-20060234164-A1 | copolymerizing norbornene monomers containing ester groups, sulonamide groups, ethers, alcohols in presence of (Acetonitrile) bis(triisopropylphosphine)palladium(acetate) tetrakis (pentafluorophenyl)borate catalyst and an optional cocatalyst lithium tetrakis(pentafluorophenyl)borate diethyl etherate | PROMERUS LLC (US) | 2006-10-19 | — | — | US | claimed |
| WO-2006091802-A2 | NORBORNENE-TYPE POLYMERS, COMPOSITIONS THEREOF AND LITHOGRAPHIC PROCESSES USING SUCH COMPOSITIONS | PROMERUS LLC (US) | 2006-08-31 | — | — | WO | claimed |
| WO-2006091523-A2 | NORBORNENE-TYPE POLYMERS, COMPOSITIONS THEREOF AND LITHOGRAPHIC PROCESSES USING SUCH COMPOSITIONS | PROMERUS LLC (US) | 2006-08-31 | — | — | WO | claimed |
| US-8329838-B2 | Norbornene-type polymers, compositions thereof and lithographic processes using such compositions | PROMERUS LLC (US) | 2012-12-11 | — | — | US | disclosed |
| EP-2510036-A2 | NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY | Promerus LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011072304-A2 | NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY | PROMERUS LLC (US) | 2011-06-16 | — | — | WO | disclosed |
| US-20110009578-A1 | Use Of A Combination Chain Transfer And Activating Agent To Control Molecular Weight And Optical Density Of Pd Catalyzed Norbornene Polymers | PROMERUS LLC (US) | 2011-01-13 | — | — | US | disclosed |
| US-7759439-B2 | Use of a combination chain transfer and activating agent to control molecular weight and optical density of Pd catalyzed norbornene polymers | PROMERUS LLC (US) | 2010-07-20 | — | — | US | disclosed |
| US-7608382-B2 | Method of controlling the differential dissolution rate of photoresist compositions, polycyclic olefin polymers and monomers used for making such polymers | PROMERUS LLC (US) | 2009-10-27 | — | — | US | disclosed |
| EP-2031007-A2 | Norbornene-type polymers, compositions thereof and lithographic processes using such compositions | Promerus LLC (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1730773-A1 | POLYMERS OF POLYCYCLIC OLEFINS HAVING A POLYHEDRAL OLIGOSILSESQUIOXANE PENDANT GROUP AND USES THEREOF | Promerus, LLC (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2006091523-A2 | NORBORNENE-TYPE POLYMERS, COMPOSITIONS THEREOF AND LITHOGRAPHIC PROCESSES USING SUCH COMPOSITIONS | PROMERUS LLC (US) | 2006-08-31 | — | — | WO | disclosed |
| EP-1597629-A2 | METHOD OF CONTROLLING THE DIFFERENTIAL DISSOLUTION RATE OF PHOTORESIST COMPOSITIONS | Promerus, LLC (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2005081306-A1 | POLYMERS OF POLYCYCLIC OLEFINS HAVING A POLYHEDRAL OLIGOSILSESQUIOXANE PENDANT GROUP AND USES THEREOF | PROMERUS, LLC (US) | 2005-09-01 | — | — | WO | disclosed |
| US-20050192409-A1 | Polymers of polycyclic olefins having a polyhedral oligosilsesquioxane pendant group and uses thereof | PROMERUS, LLC | 2005-09-01 | — | — | US | disclosed |
| WO-2004077160-A2 | METHOD OF CONTROLLING THE DIFFERENTIAL DISSOLUTION RATE OF PHOTORESIST COMPOSITIONS | PROMERUS, LLC (US) | 2004-09-10 | — | — | WO | disclosed |
| US-20040166436-A1 | Method of controlling the differential dissolution rate of photoresist compositions, polycyclic olefin polymers and monomers used for making such polymers | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2004-08-26 | — | — | US | disclosed |