Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 12/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CALML3 | P27482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484108 | 1.00 | GRM2 (0.60) | GRM2MAOAMAOBCALML3 | |
| SCHEMBL11227524 | 0.88 | MAOA (0.61) | GRM2MAOAMAOBCALML3 | |
| SCHEMBL11230811 | 0.87 | GRM2 (0.65) | GRM2 | |
| SCHEMBL10858072 | 0.87 | GRM2 (0.56) | GRM2MAOAMAOBCALML3 | |
| SCHEMBL9468120 | 0.86 | GRM2 (0.67) | GRM2 | |
| SCHEMBL9464025 | 0.86 | GRM2 (0.67) | GRM2 | |
| SCHEMBL9482670 | 0.86 | GRM2 (0.67) | GRM2 | |
| SCHEMBL9482668 | 0.85 | GRM2 (0.53) | GRM2MAOAMAOB | |
| SCHEMBL9482662 | 0.85 | GRM2 (0.53) | GRM2MAOAMAOB | |
| SCHEMBL27350721 | 0.85 | GRM2 (0.54) | GRM2MAOAMAOBCALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5235063-A | Acetal derivatives of 3-aryl-2-oxazolidine; antidepressants | DELALANDE S.A. (FR) | 1993-08-10 | — | — | US | disclosed |
| US-5196543-A | Antidepressants, tranquilizers | DELALANDE S.A. (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5171747-A | Anxiolytic agents, antidepressants | DELALANDE S.A. (FR) | 1992-12-15 | — | — | US | disclosed |
| US-5036091-A | Psychotropic drugs | DELALANDE S.A. (FR) | 1991-07-30 | — | — | US | disclosed |
| US-5036090-A | Antidepressants | DELALANDE S.A. (FR) | 1991-07-30 | — | — | US | disclosed |
| US-4178382-A | INSECTICIDE FOR COTTON | UNIROYAL, INC. (US) | 1979-12-11 | — | — | US | disclosed |
| US-4150029-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1979-04-17 | — | — | US | disclosed |