Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 1/20 | 0.79 |
| ▸ | TK1 | P04183 | 3/20 | 0.61 |
| ▸ | DTYMK | P23919 | 1/20 | 0.56 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484973 | 0.92 | TK2 (0.75) | TK2TK1DTYMKLMNATSHR | |
| SCHEMBL26661810 | 0.88 | TK2 (0.76) | TK2TK1DTYMKRNASE1LMNA | |
| SCHEMBL7212402 | 0.88 | TK2 (0.75) | TK2TK1DTYMKLMNATSHR | |
| SCHEMBL7212404 | 0.88 | TK2 (0.75) | TK2TK1DTYMKLMNATSHR | |
| SCHEMBL9484733 | 0.87 | TK2 (0.74) | TK2TK1DTYMKLMNATSHR | |
| SCHEMBL2056542 | 0.86 | TK2 (0.73) | TK2TK1DTYMKLMNATSHR | |
| SCHEMBL2056538 | 0.86 | TK2 (0.73) | TK2TK1DTYMKLMNATSHR | |
| SCHEMBL11600089 | 0.85 | TK2 (0.71) | TK2TK1DTYMKLMNATSHR | |
| SCHEMBL11600096 | 0.85 | TK2 (0.71) | TK2TK1DTYMKLMNATSHR | |
| SCHEMBL12657666 | 0.84 | TK2 (0.67) | TK2TK1LMNATSHRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212161-A | Antitumor | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) (FR) | 1993-05-18 | — | — | US | disclosed |