Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 7/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727289 | 0.80 | ATM (0.44) | HPGDNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL9483959 | 0.77 | HTT (0.45) | HPGDNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL9483366 | 0.76 | SRD5A2 (0.41) | HPGDNPC1SMN1; SMN2HTTKMT2A | |
| SCHEMBL5727593 | 0.75 | ERCC5 (0.40) | ALDH1A1 | |
| SCHEMBL9484049 | 0.75 | SRD5A2 (0.45) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL5727378 | 0.75 | MAPT (0.39) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9685893 | 0.75 | CNR2 (0.36) | CNR2 | |
| SCHEMBL9482917 | 0.73 | HPGD (0.45) | HPGDNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL9483334 | 0.73 | ALDH1A1 (0.48) | HPGDNPC1RAB9AHTTMAPT | |
| SCHEMBL9483054 | 0.71 | ATM (0.41) | HPGDNPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240949-A | Analgesics, blood lipid normalizing | ADIR ET COMPAGNIE (FR) | 1993-08-31 | — | — | US | disclosed |
| US-5166353-A | Analgesics, anticholesterol agents, anticoagulants, antilipemic agents | ADIR ET COMPAGNIE (FR) | 1992-11-24 | — | — | US | disclosed |
| US-5162350-A | Analgesics; nontoxic; side effect reduction | ADIR ET COMPAGNIE (FR) | 1992-11-10 | — | — | US | disclosed |
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |