Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | ALB | P02768 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TK2 | O00142 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Amino- 3-Deoxythymidine SCHEMBL1415407 | 1.00 | TK1 (0.68) | TK1LMNATSHRALBPKM | |
| 3-Amino- 3-Deoxythymidine SCHEMBL19831521 | 1.00 | TK1 (0.68) | TK1LMNATSHRALBPKM | |
| 3-Amino- 3-Deoxythymidine SCHEMBL17011263 | 1.00 | TK1 (0.68) | TK1LMNATSHRALBPKM | |
| 3-Amino- 3-Deoxythymidine SCHEMBL13497992 | 1.00 | TK1 (0.68) | TK1LMNATSHRALBPKM | |
| 3-Amino- 3-Deoxythymidine SCHEMBL20099120 | 1.00 | TK1 (0.68) | TK1LMNATSHRALBPKM | |
| 3-Amino- 3-Deoxythymidine SCHEMBL13394196 | 1.00 | TK1 (0.68) | TK1LMNATSHRALBPKM | |
| 3-Amino- 3-Deoxythymidine SCHEMBL1415408 | 1.00 | TK1 (0.68) | TK1LMNATSHRALBPKM | |
| SCHEMBL10792074 | 0.89 | TK1 (0.61) | TK1LMNATSHRALBPKM | |
| SCHEMBL10792081 | 0.89 | TK1 (0.61) | TK1LMNATSHRALBPKM | |
| SCHEMBL22819197 | 0.89 | TK1 (0.61) | TK1LMNATSHRALBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968788-A | DRUG DELIVERY, ANTITUMOR AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1990-11-06 | — | — | US | claimed |
| US-5212161-A | Antitumor | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) (FR) | 1993-05-18 | — | — | US | disclosed |
| WO-1990008155-A1 | BIOLOGICALLY REVERSIBLE PHOSPHATE AND PHOSPHONATE PROTECTIVE GROUPS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1990-07-26 | — | — | WO | disclosed |