Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304292 | 0.96 | CHRM1 (0.55) | CHRM1ALDH1A1RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL13321596 | 0.96 | CHRM1 (0.55) | CHRM1ALDH1A1RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL22115782 | 0.82 | CHRM1 (0.45) | CHRM1ALDH1A1RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL3843370 | 0.81 | KMT2A (0.50) | CHRM1ALDH1A1KDM4ESMN1; SMN2THRB | |
| SCHEMBL304743 | 0.80 | RECQL (0.44) | CHRM1ALDH1A1RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL304742 | 0.80 | RECQL (0.44) | CHRM1ALDH1A1RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL21712561 | 0.80 | SMN1; SMN2 (0.45) | CHRM1ALDH1A1RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL19917124 | 0.79 | KMT2A (0.50) | ALDH1A1KDM4ESMN1; SMN2THRBATM | |
| SCHEMBL8958031 | 0.79 | GAA (0.49) | CHRM1ALDH1A1RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL11533240 | 0.78 | HTR2C (0.59) | CHRM1ALDH1A1KDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210284-A | CONTINUOUS PROCESS FOR THE PREPARATION OF ISOCYANATES FROM URETHANES | ENICHEM SYNTHESIS S.P.A. (IT) | 1993-05-11 | — | — | US | claimed |
| US-5210284-A | CONTINUOUS PROCESS FOR THE PREPARATION OF ISOCYANATES FROM URETHANES | ENICHEM SYNTHESIS S.P.A. (IT) | 1993-05-11 | — | — | US | disclosed |