Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 4/20 | 0.47 |
| ▸ | NAT1 | P18440 | 4/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAX | P61244 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049913 | 0.79 | PTP4A3 (0.66) | PTP4A3NAT1MYCMAXMEN1 | |
| SCHEMBL8049909 | 0.79 | PTP4A3 (0.66) | PTP4A3NAT1MYCMAXMEN1 | |
| SCHEMBL27412321 | 0.71 | CISD1 (0.57) | NAT1MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8307763 | 0.71 | NAT1 (0.61) | PTP4A3NAT1MYCMAXMEN1 | |
| SCHEMBL8713697 | 0.71 | NAT1 (0.61) | PTP4A3NAT1MYCMAXMEN1 | |
| SCHEMBL8171894 | 0.69 | NAT1 (0.59) | PTP4A3NAT1MEN1ALDH1A1LMNA | |
| SCHEMBL18102998 | 0.69 | NAT1 (0.59) | PTP4A3NAT1MEN1ALDH1A1LMNA | |
| SCHEMBL9484464 | 0.68 | MEN1 (0.41) | PTP4A3NAT1MYCMAXMEN1 | |
| SCHEMBL8708264 | 0.68 | PDE4B (0.70) | NAT1MEN1ALDH1A1LMNAGAA | |
| SCHEMBL8309755 | 0.68 | PDE4B (0.70) | NAT1MEN1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526598-A1 | NEW PHARMACOLOGICALLY ACTIVE CATECHOL DERIVATIVES. | ORION YHTYMAE OY (FI) | 1993-02-10 | — | — | EP | claimed |
| WO-1991017151-A1 | NEW PHARMACOLOGICALLY ACTIVE CATECHOL DERIVATIVES | Orion-Yhtymä Oy (FI) | 1991-11-14 | — | — | WO | claimed |