Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.62 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.62 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484156 | 0.92 | P2RX7 (0.83) | P2RX7ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9588593 | 0.91 | P2RX7 (1.00) | P2RX7ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9483287 | 0.90 | P2RX7 (0.88) | P2RX7ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9483558 | 0.90 | P2RX7 (0.68) | P2RX7ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9484447 | 0.89 | P2RX7 (0.66) | P2RX7ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9484610 | 0.89 | P2RX7 (0.94) | P2RX7ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9483116 | 0.88 | P2RX7 (0.80) | P2RX7ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9482967 | 0.88 | P2RX7 (0.68) | P2RX7ALDH1A1SMN1; SMN2LMNAMAPT | |
| Bromide SCHEMBL9483297 | 0.87 | P2RX7 (0.79) | P2RX7ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9484310 | 0.87 | P2RX7 (0.81) | P2RX7ALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |