Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485127 | 0.90 | CYP2D6 (0.72) | CYP2D6 | |
| SCHEMBL8613592 | 0.89 | CYP2D6 (0.66) | CYP2D6 | |
| SCHEMBL8589775 | 0.89 | CYP2D6 (0.71) | CYP2D6 | |
| SCHEMBL8588945 | 0.89 | CYP2D6 (0.71) | CYP2D6 | |
| SCHEMBL7776412 | 0.89 | CYP2D6 (0.73) | CYP2D6 | |
| SCHEMBL8590008 | 0.87 | CYP2D6 (0.66) | CYP2D6 | |
| SCHEMBL6360833 | 0.87 | GHSR (0.75) | CYP2D6 | |
| SCHEMBL8588853 | 0.86 | CYP2D6 (0.67) | CYP2D6 | |
| SCHEMBL30966673 | 0.85 | NCOA1 (0.70) | CYP2D6 | |
| SCHEMBL3059317 | 0.85 | NCOA1 (0.70) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290558-B1 | ANTIFOLATE AGENTS | BTG INTERNATIONAL LIMITED (GB) | 1993-06-16 | — | — | EP | claimed |
| EP-0290558-B1 | ANTIFOLATE AGENTS | BTG INTERNATIONAL LIMITED (GB) | 1993-06-16 | — | — | EP | disclosed |
| US-4992444-A | Antitumor agents, skin disorders | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1991-02-12 | — | — | US | disclosed |