Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.38 |
| ▸ | BID | P55957 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484753 | 0.87 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9484155 | 0.80 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9364232 | 0.76 | PTGER1 (0.42) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL8937896 | 0.76 | PTGER1 (0.42) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9430238 | 0.71 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9484791 | 0.70 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL8937745 | 0.69 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9364503 | 0.69 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9856680 | 0.67 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1FAAHCES1 | |
| SCHEMBL9559793 | 0.67 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532674-A4 | LEUKOTRIENE ANTAGONISTS | — | 1993-04-07 | — | — | EP | claimed |
| EP-0532674-A1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-24 | — | — | EP | claimed |
| WO-1991018889-A1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | claimed |
| EP-0532674-A4 | LEUKOTRIENE ANTAGONISTS | — | 1993-04-07 | — | — | EP | disclosed |
| EP-0532674-A1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018889-A1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |