Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364503 | 1.00 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 | |
| SCHEMBL9428739 | 0.97 | PTGER1 (0.46) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 | |
| SCHEMBL9856680 | 0.92 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1 | |
| SCHEMBL9429346 | 0.85 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1 | |
| SCHEMBL9364884 | 0.85 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 | |
| SCHEMBL9364882 | 0.85 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 | |
| SCHEMBL9364232 | 0.80 | PTGER1 (0.42) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 | |
| SCHEMBL9503595 | 0.80 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1 | |
| SCHEMBL8937896 | 0.80 | PTGER1 (0.42) | CYSLTR2CYSLTR1PLA2G4BPLA2G4APTGER1 | |
| SCHEMBL9428630 | 0.80 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675877-A4 | A PROCESS FOR PREPARING SULFONES. | SMITHKLINE BEECHAM CORP (US) | 1996-07-31 | — | — | EP | claimed |
| EP-0675877-A1 | A PROCESS FOR PREPARING SULFONES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-11 | — | — | EP | claimed |
| WO-1994021603-A1 | A PROCESS FOR PREPARING SULFONES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-09-29 | — | — | WO | claimed |
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | claimed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | claimed |
| EP-0675877-A4 | A PROCESS FOR PREPARING SULFONES. | SMITHKLINE BEECHAM CORP (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0675877-A1 | A PROCESS FOR PREPARING SULFONES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994021603-A1 | A PROCESS FOR PREPARING SULFONES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-09-29 | — | — | WO | disclosed |
| US-5314918-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0403249-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |