SCHEMBL9485754

SCHEMBL9485754

COc1ccc(N2CC(CN3CCC(OC(C)=O)(c4ccc5c(c4)OCO5)CC3)OC2=O)cc1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Panamesine SCHEMBL7297073 0.89 SIGMAR1 (1.00) SIGMAR1
Panamesine SCHEMBL637459 0.89 SIGMAR1 (1.00) SIGMAR1
SCHEMBL7295110 0.89 SIGMAR1 (0.78) SIGMAR1
Panamesine SCHEMBL467011 0.88 SIGMAR1 (0.98) SIGMAR1
SCHEMBL9487085 0.87 SIGMAR1 (0.78) SIGMAR1
SCHEMBL7299816 0.86 SIGMAR1 (0.80) SIGMAR1
SCHEMBL9486095 0.85 SIGMAR1 (0.77) SIGMAR1
SCHEMBL7299061 0.85 SIGMAR1 (0.74) SIGMAR1
SCHEMBL7299281 0.81 SIGMAR1 (0.84) SIGMAR1
SCHEMBL9486880 0.81 SIGMAR1 (1.00) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5232931-A OXAZOLIDINONES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-08-03 US disclosed