Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487123 | 0.86 | BCHE (0.50) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| SCHEMBL9486120 | 0.85 | KCNH2 (0.48) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| SCHEMBL9486208 | 0.84 | ESR1 (0.68) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL9486402 | 0.83 | ABCB11 (0.69) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL9486674 | 0.80 | CNR2 (0.50) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| SCHEMBL31505225 | 0.79 | ESR1 (0.72) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| SCHEMBL282404 | 0.79 | ESR1 (0.72) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| SCHEMBL9485662 | 0.78 | ESR1 (0.56) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL14633803 | 0.78 | ABCB11 (0.72) | CHRM2HTR1ADRD3SLC6A3KCNH2 | |
| SCHEMBL9047439 | 0.78 | OXER1 (0.48) | CHRM2HTR1ADRD3SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223510-A | ALKYLAMINOALKYL DERIVATIVES OF BENZOFURAN, BENZOTHIOPHENE, INDOLE AND INDOLIZINE, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1993-06-29 | — | — | US | disclosed |