⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486823 | 1.00 | — | — | |
| SCHEMBL9486813 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL23296786 | 0.98 | GABRP (0.43) | — | |
| Hydrochloric Acid SCHEMBL23296788 | 0.98 | GABRP (0.43) | — | |
| SCHEMBL9486312 | 0.82 | THPO (0.37) | — | |
| SCHEMBL9487885 | 0.82 | THPO (0.37) | — | |
| SCHEMBL9486317 | 0.82 | THPO (0.37) | — | |
| SCHEMBL2952521 | 0.80 | — | — | |
| SCHEMBL25095512 | 0.79 | — | — | |
| SCHEMBL9488694 | 0.79 | SLC7A5 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691969-B2 | Pyridazinones as PARP7 inhibtors | RIBON THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-11691969-B2 | Pyridazinones as PARP7 inhibtors | RIBON THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-20210130342-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | ANKURA TRUST COMPANY, LLC, AS COLLATERAL TRUSTEE | 2021-05-06 | — | — | US | disclosed |
| WO-2021087025-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | RIBON THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | WO | disclosed |
| EP-0350002-B1 | DIPHOSPHONIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THOSE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-01-13 | — | — | EP | disclosed |
| US-5002937-A | Diphosphonic acid alkyloxyalkylamines for bone disorders | BOEHRINGER MANNHEIM GMBH (DE) | 1991-03-26 | — | — | US | disclosed |
| EP-0350002-A1 | Diphosphonic-acid derivatives, process for their preparation and medicines containing those compounds | Roche Diagnostics GmbH (DE) | 1990-01-10 | — | — | EP | disclosed |