Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633039 | 1.00 | FOLH1 (0.38) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL218863 | 0.80 | FOLH1 (0.39) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL5729609 | 0.80 | FOLH1 (0.39) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL1023301 | 0.79 | FOLH1 (0.32) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL31510814 | 0.78 | ACE (0.42) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL313185 | 0.77 | ACE (0.41) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL27624628 | 0.77 | ACE (0.41) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL8735 | 0.75 | FOLH1 (0.46) | FOLH1KDM4EMAPTBLMSMN1; SMN2 | |
| SCHEMBL5319987 | 0.75 | KMT2A (0.47) | FOLH1ALOX15BLMRIMKLANAALAD2 | |
| SCHEMBL8734 | 0.75 | FOLH1 (0.46) | FOLH1KDM4EMAPTBLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367033-B1 | S-DIFLUOROMETHYLHOMOCYSTEINES, PREPARATION PROCESS, AND INSECTICIDAL COMPOSITIONS | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-02-10 | — | — | EP | disclosed |
| US-5166425-A | Reaction of homocysteine and sodium salt with chlorodifluoro methane in the presence of potassium tert-butoxide | SHIONOGI & CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0367033-A1 | S-Difluoromethylhomocysteines, preparation process, and insecticidal compositions | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1990-05-09 | — | — | EP | disclosed |