Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20919279 | 0.94 | LMNA (0.46) | LMNAALDH1A1HTTCYP1A2MAPT | |
| SCHEMBL29731800 | 0.94 | LMNA (0.46) | LMNAALDH1A1HTTCYP1A2MAPT | |
| SCHEMBL15655133 | 0.93 | LMNA (0.50) | LMNAALDH1A1HTTCYP1A2MAPT | |
| SCHEMBL142795 | 0.90 | LMNA (0.48) | LMNAALDH1A1HTTCYP1A2MAPT | |
| SCHEMBL12348879 | 0.87 | LMNA (0.45) | LMNAALDH1A1HTTCYP1A2MAPT | |
| SCHEMBL31484680 | 0.85 | CYP1A2 (0.57) | LMNAALDH1A1HTTCYP1A2MAPT | |
| SCHEMBL24511038 | 0.84 | LMNA (0.48) | LMNAALDH1A1HTTCYP1A2MAPT | |
| SCHEMBL2936378 | 0.83 | MEN1 (0.45) | LMNAALDH1A1HTTCYP1A2MAPT | |
| SCHEMBL11304603 | 0.81 | LMNA (0.46) | LMNAALDH1A1HTTCYP1A2MAPT | |
| SCHEMBL6472472 | 0.81 | HTT (0.40) | LMNAALDH1A1HTTCYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058833-A1 | NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF | 国立大学法人広島大学 (JP) | 2010-05-27 | — | — | WO | disclosed |
| US-5256742-A | Preparation of poly(arylene sulfide)s from poly(arylene sulfide disulfide) | PHILLIPS PETROLEUM COMPANY (US) | 1993-10-26 | — | — | US | disclosed |
| US-4370470-A | Multistage, agitated contactor and its use in continuous production of arylene sulfide polymer | PHILLIPS PETROLEUM COMPANY (US) | 1983-01-25 | — | — | US | disclosed |
| EP-0044184-A2 | Blend of polyarylene sulfide and wholly aromatic polyester | CELANESE CORPORATION (US) | 1982-01-20 | — | — | EP | disclosed |
| US-4276397-A | IMPROVED PROCESSABILITY TO FORM MOLDED ARTICLES | CELANESE CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |