Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532155 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNACYP2C9ALOX15HSD17B10 | |
| SCHEMBL7796811 | 0.68 | ALDH1A1 (0.46) | ALDH1A1LMNACYP2C9ALOX15HTT | |
| SCHEMBL8536663 | 0.67 | MAPK1 (0.41) | — | |
| SCHEMBL9283906 | 0.65 | ALDH1A1 (0.38) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL7703145 | 0.65 | ALDH1A1 (0.40) | ALDH1A1LMNACYP2C9ALOX15HTT | |
| SCHEMBL8532773 | 0.65 | ALDH1A1 (0.38) | ALDH1A1LMNACYP2C9ALOX15HTT | |
| SCHEMBL7563154 | 0.65 | MAOB (0.46) | ALDH1A1HSD17B10 | |
| SCHEMBL7855632 | 0.64 | HSD17B10 (0.57) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL7560742 | 0.64 | CACNA1A (0.43) | ALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL8933311 | 0.64 | ALDH1A1 (0.40) | ALDH1A1LMNACYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216002-A | Using benzyl substituted rhodanine derivatives as pure enantiomeric form | ELI LILLY AND COMPANY (US) | 1993-06-01 | — | — | US | disclosed |