Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 4/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30327476 | 1.00 | SIGMAR1 (0.46) | SIGMAR1CYP2C9TSHRCYP2C19CYP3A4 | |
| SCHEMBL20245480 | 0.82 | KDM4E (0.40) | MTNR1AMTNR1B | |
| SCHEMBL13627306 | 0.81 | TACR1 (0.43) | SIGMAR1CYP2C9TSHRCYP2C19CYP3A4 | |
| SCHEMBL11033750 | 0.81 | SIGMAR1 (0.46) | SIGMAR1CYP2C9TSHRCYP2C19CYP3A4 | |
| SCHEMBL3431949 | 0.78 | POLA1 (0.49) | SIGMAR1CYP2C9TSHRCYP2C19CYP3A4 | |
| SCHEMBL9487217 | 0.78 | SMN1; SMN2 (0.45) | SIGMAR1CYP3A4MTNR1AMTNR1BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11647752 | 0.77 | SMN1; SMN2 (0.44) | SIGMAR1CYP3A4MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL28735232 | 0.77 | SIGMAR1 (0.45) | SIGMAR1CYP2C9TSHRCYP2C19CYP3A4 | |
| SCHEMBL29118401 | 0.77 | SIGMAR1 (0.45) | SIGMAR1CYP2C9TSHRCYP2C19CYP3A4 | |
| SCHEMBL9487477 | 0.76 | POLA1 (0.42) | SIGMAR1CYP2C9TSHRCYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384917-B1 | (+)-OR (+)-1-(2-N-SUBSTITUTED AMINOETHYL)-1-METHYL-7-METHOXY-1,2,3,4-TETRAHYDRONAPHTHALENE, AND PROCESS FOR PRODUCTION THEREOF | Nihon Iyakuhin Kogyo Co., Ltd. (JP) | 1993-01-13 | — | — | EP | claimed |
| EP-0384917-A1 | (+)-Or (+)-1-(2-N-substituted aminoethyl)-1-methyl-7-methoxy-1,2,3,4-tetrahydronaphthalene, and process for production thereof | Nihon Iyakuhin Kogyo Co., Ltd. (JP) | 1990-09-05 | — | — | EP | claimed |
| CN-113087622-B | Preparation method of eptazocine intermediate | 广州一品红制药有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-113087622-B | Preparation method of eptazocine intermediate | 广州一品红制药有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-113087622-A | Preparation method of eptazocine intermediate | 广州一品红制药有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-113087622-A | Preparation method of eptazocine intermediate | 广州一品红制药有限公司 | 2021-07-09 | — | — | CN | disclosed |
| EP-0384917-B1 | (+)-OR (+)-1-(2-N-SUBSTITUTED AMINOETHYL)-1-METHYL-7-METHOXY-1,2,3,4-TETRAHYDRONAPHTHALENE, AND PROCESS FOR PRODUCTION THEREOF | Nihon Iyakuhin Kogyo Co., Ltd. (JP) | 1993-01-13 | — | — | EP | disclosed |
| EP-0384917-A1 | (+)-Or (+)-1-(2-N-substituted aminoethyl)-1-methyl-7-methoxy-1,2,3,4-tetrahydronaphthalene, and process for production thereof | Nihon Iyakuhin Kogyo Co., Ltd. (JP) | 1990-09-05 | — | — | EP | disclosed |