Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050121 | 0.86 | SLC5A2 (0.40) | SLC6A4SMN1; SMN2ALDH1A1POLBMAOA | |
| SCHEMBL2048163 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1POLBALOX12HTT | |
| SCHEMBL9486538 | 0.81 | DAO (0.38) | SMN1; SMN2ALDH1A1POLBALOX12HTT | |
| SCHEMBL2253674 | 0.81 | DAO (0.47) | SMN1; SMN2ALDH1A1POLBALOX12HTT | |
| SCHEMBL2253149 | 0.80 | SLC6A4 (0.41) | SLC6A4SMN1; SMN2ALDH1A1MAOAGSK3B | |
| SCHEMBL9486577 | 0.79 | DAO (0.49) | SMN1; SMN2ALDH1A1POLBALOX12HTT | |
| SCHEMBL9487098 | 0.79 | DAO (0.48) | SMN1; SMN2ALDH1A1POLBDAO | |
| SCHEMBL9486357 | 0.78 | POLB (0.36) | SMN1; SMN2ALDH1A1POLBALOX12HTT | |
| SCHEMBL2255973 | 0.78 | CYP1A2 (0.48) | SMN1; SMN2ALDH1A1POLBALOX12HTT | |
| SCHEMBL9486036 | 0.78 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1POLBALOX12HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264451-A | Process for treating hyperglycemia using trifluoromethyl substituted 3H-pyrazol-3-ones | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-11-23 | — | — | US | disclosed |