Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525936 | 0.96 | F2 (0.51) | F2KMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9487767 | 0.95 | F2 (0.50) | F2KMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9485858 | 0.95 | F2 (0.50) | F2KMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9302657 | 0.95 | F2 (0.54) | F2KMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9302661 | 0.95 | F2 (0.54) | F2KMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL8211820 | 0.95 | F2 (0.54) | F2KMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9487871 | 0.94 | F2 (0.49) | F2KMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9486380 | 0.94 | F2 (0.49) | F2KMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9488379 | 0.94 | F2 (0.49) | F2KMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9486941 | 0.94 | F2 (0.49) | F2KMT2AHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2279649-A | — | — | None | — | — | JP | disclosed |
| US-5190692-A | FOUR RING ESTERS AND ETHERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| JP-H02279649-A | FOUR RINGS ESTER COMPOUND AND ETHER COMPOUND | MERCK PATENT GMBH | 1990-11-15 | — | — | JP | disclosed |