Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486380 | 1.00 | F2 (0.49) | F2THRBTHRAKMT2AHTT | |
| SCHEMBL9486941 | 1.00 | F2 (0.49) | F2THRBTHRAKMT2AHTT | |
| SCHEMBL9487871 | 1.00 | F2 (0.49) | F2THRBTHRAKMT2AHTT | |
| SCHEMBL17809772 | 0.98 | F2 (0.51) | F2THRBTHRAKMT2AHTT | |
| SCHEMBL9487767 | 0.97 | F2 (0.50) | F2THRBTHRAKMT2AHTT | |
| SCHEMBL9485858 | 0.97 | F2 (0.50) | F2THRBTHRAKMT2AHTT | |
| SCHEMBL9486971 | 0.94 | F2 (0.54) | F2THRBTHRAKMT2AHTT | |
| SCHEMBL9301959 | 0.93 | THRB (0.53) | F2THRBTHRAKMT2AHTT | |
| SCHEMBL2827602 | 0.93 | THRB (0.53) | F2THRBTHRAKMT2AHTT | |
| SCHEMBL9301954 | 0.93 | THRB (0.53) | F2THRBTHRAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190692-A | FOUR RING ESTERS AND ETHERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |