Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483650 | 0.95 | MAPK14 (0.45) | MAPK14SERPINE1ALDH1A1HTTMEN1 | |
| SCHEMBL9484793 | 0.92 | HTT (0.49) | SERPINE1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9484182 | 0.91 | MAPK14 (0.44) | MAPK14ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9484446 | 0.90 | HDAC6 (0.47) | SERPINE1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9483626 | 0.89 | MEN1 (0.53) | MAPK14MEN1KMT2AMLYCDPPARG | |
| SCHEMBL9483393 | 0.89 | THRB (0.45) | SERPINE1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9483952 | 0.88 | TDP1 (0.47) | SERPINE1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9484821 | 0.87 | CCR1 (0.44) | SERPINE1ALDH1A1HTTTHRBHDAC6 | |
| SCHEMBL9483312 | 0.86 | THRB (0.47) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL9483291 | 0.85 | MAPK14 (0.43) | MAPK14SERPINE1ALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5191089-A | Herbicides for weeds that don't harm soybeans, corn, cotton or barley | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |