Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414880 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9487495 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9486798 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9486739 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9486735 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9487852 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9486433 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9487845 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL9486428 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHPGDALOX15 | |
| SCHEMBL10875341 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316786-B1 | TRIALKYL AMINE SALTS OF 1,1-DICYANO-2-HYDROXY-3-CHLOROPROP-1-ENE, AND PROCESS FOR THE PREPARATION OF 2-AMINO-4-CHLORO-3-CYANO-5-FORMYL THIOPHENE | BASF Aktiengesellschaft (DE) | 1991-11-27 | — | — | EP | claimed |
| EP-0316786-A1 | Trialkyl amine salts of 1,1-dicyano-2-hydroxy-3-chloroprop-1-ene, and process for the preparation of 2-amino-4-chloro-3-cyano-5-formyl thiophene | BASF Aktiengesellschaft (DE) | 1989-05-24 | — | — | EP | claimed |
| JP-1153668-A | — | — | None | — | — | JP | disclosed |
| US-5206375-A | Thiophene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-27 | — | — | US | disclosed |
| EP-0316786-B1 | TRIALKYL AMINE SALTS OF 1,1-DICYANO-2-HYDROXY-3-CHLOROPROP-1-ENE, AND PROCESS FOR THE PREPARATION OF 2-AMINO-4-CHLORO-3-CYANO-5-FORMYL THIOPHENE | BASF Aktiengesellschaft (DE) | 1991-11-27 | — | — | EP | disclosed |
| US-4980495-A | Chemical intermediates for the synthesis of 2-amino-4-chloro-3-cyano-5-formylthiophene or other heterocyclic compounds | BASF AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0251114-B1 | THIENOTHIOPHENE DYES | BASF Aktiengesellschaft (DE) | 1990-05-02 | — | — | EP | disclosed |
| US-4843153-A | Azo dyes containing thienothiophene radicals as radicals of the diazo component | BASF AKTIENGESELLSCHAFT (DE) | 1989-06-27 | — | — | US | disclosed |
| JP-H01153668-A | TRIALKYLAMINE SALT OF 3-CHLORO-1,1-DICYANO-2-HYDROXY-1-PROPENE AND PREPARATION OF 2-AMINO-4-CHLORO-3-CYANO-5-FORMYLTHIOPHENE THEREFROM | BASF AG | 1989-06-15 | — | — | JP | disclosed |
| EP-0193885-B1 | THIOPHENE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1989-06-14 | — | — | EP | disclosed |
| EP-0316786-A1 | Trialkyl amine salts of 1,1-dicyano-2-hydroxy-3-chloroprop-1-ene, and process for the preparation of 2-amino-4-chloro-3-cyano-5-formyl thiophene | BASF Aktiengesellschaft (DE) | 1989-05-24 | — | — | EP | disclosed |
| EP-0251114-A2 | Thienothiophene dyes | BASF Aktiengesellschaft (DE) | 1988-01-07 | — | — | EP | disclosed |
| EP-0193885-A1 | Thiophene derivatives | BASF Aktiengesellschaft (DE) | 1986-09-10 | — | — | EP | disclosed |