Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mcpb SCHEMBL8584416 | 0.93 | TSHR (0.66) | HPGDRAB9ANLRP1MAPTTSHR | |
| Mcpb SCHEMBL9522487 | 0.88 | TSHR (0.73) | HPGDRAB9ANLRP1MAPTTSHR | |
| (R)-Dichlorprop SCHEMBL29725135 | 0.86 | TSHR (0.73) | HPGDMAPTTSHRHTR2AHTR2C | |
| Rac-Dichlorprop SCHEMBL54510 | 0.86 | TSHR (0.73) | HPGDMAPTTSHRHTR2AHTR2C | |
| (S)-Dichlorprop SCHEMBL29426455 | 0.86 | TSHR (0.73) | HPGDMAPTTSHRHTR2AHTR2C | |
| SCHEMBL116448 | 0.86 | RAB9A (0.78) | HPGDRAB9ANLRP1MAPTTSHR | |
| (R)-Dichlorprop SCHEMBL55175 | 0.86 | TSHR (0.73) | HPGDMAPTTSHRHTR2AHTR2C | |
| Rac-Dichlorprop SCHEMBL3017921 | 0.86 | TSHR (0.73) | HPGDMAPTTSHRHTR2AHTR2C | |
| (S)-Dichlorprop SCHEMBL1535831 | 0.86 | TSHR (0.73) | HPGDMAPTTSHRHTR2AHTR2C | |
| SCHEMBL29364868 | 0.86 | RAB9A (0.78) | HPGDRAB9ANLRP1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262393-B1 | DERIVATIVES OF ARYLOXYCARBONIC ACIDS, THEIR PREPARATION AND THEIR USE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-01-07 | — | — | EP | disclosed |