Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13662396 | 0.87 | MAPT (0.46) | MAPTLMNAMDM2MDM4SMN1; SMN2 | |
| SCHEMBL636993 | 0.87 | MAPT (0.46) | MAPTLMNAMDM2MDM4SMN1; SMN2 | |
| SCHEMBL629505 | 0.83 | MAPT (0.48) | MAPTLMNAMDM2MDM4SMN1; SMN2 | |
| SCHEMBL629506 | 0.83 | MAPT (0.48) | MAPTLMNAMDM2MDM4SMN1; SMN2 | |
| SCHEMBL1273130 | 0.83 | MAPT (0.48) | MAPTLMNAMDM2MDM4SMN1; SMN2 | |
| SCHEMBL9298448 | 0.81 | GAA (0.51) | MAPTLMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3858960 | 0.81 | GAA (0.51) | MAPTLMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL2549625 | 0.81 | GAA (0.51) | MAPTLMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28837932 | 0.78 | MAPT (0.59) | MAPTLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6524082 | 0.76 | MAPT (0.50) | MAPTLMNASMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198397-B1 | METHOD OF PRODUCING L-PHENYLALANINE | KURARAY CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| US-4743547-A | PURITY, ENZYME HYDROLYSIS | KURARAY CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0198397-A2 | Method of producing L-phenylalanine | KURARAY CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |