Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.35 |
| ▸ | CAD | P27708 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10949228 | 1.00 | HTT (0.70) | HTTKMT2AITGA4CADMAPT | |
| SCHEMBL9662670 | 0.83 | HTT (0.57) | HTTKMT2AITGA4 | |
| SCHEMBL2333909 | 0.82 | HTT (1.00) | HTTKMT2AMAPTGAAKDM4E | |
| SCHEMBL24668935 | 0.79 | HTT (0.45) | HTTKMT2AITGA4 | |
| Limazocic SCHEMBL1230921 | 0.78 | HTT (0.58) | HTTKMT2AITGA4CADMAPT | |
| Limazocic SCHEMBL9326335 | 0.78 | HTT (0.58) | HTTKMT2AITGA4CADMAPT | |
| Limazocic SCHEMBL9329801 | 0.78 | HTT (0.58) | HTTKMT2AITGA4CADMAPT | |
| SCHEMBL24378491 | 0.76 | HTT (0.45) | HTTKMT2AGAALMNABLM | |
| SCHEMBL24378313 | 0.76 | HTT (0.45) | HTTKMT2AGAALMNABLM | |
| SCHEMBL24378532 | 0.74 | HSD17B10 (0.43) | HTTKMT2ALMNABLMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134272-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF DERMAL AND OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2024-06-27 | — | — | WO | disclosed |
| US-20230241675-A1 | COMPOSITIONS, COMPRISING PLATELET-SHAPED TRANSITION METAL PARTICLES | BASF SE (DE) | 2023-08-03 | — | — | US | disclosed |
| EP-0326326-B1 | CYSTEINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| US-4517123-A | Cysteine derivatives of disulfide form | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-05-14 | — | — | US | disclosed |