Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743976 | 0.82 | USP2 (0.44) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL12240998 | 0.77 | KDM4E (0.40) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL12208814 | 0.76 | KDM4E (0.39) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL118999 | 0.76 | KDM4E (0.39) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL9549503 | 0.74 | KDM4E (0.38) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL13242117 | 0.73 | CA12 (0.41) | ALDH1A1LMNA | |
| SCHEMBL25520674 | 0.72 | USP2 (0.48) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL2759911 | 0.72 | PTGS2 (0.36) | ALDH1A1TSHR | |
| SCHEMBL3462689 | 0.72 | KDM4E (0.43) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL18020651 | 0.72 | KDM4E (0.39) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5235063-A | Acetal derivatives of 3-aryl-2-oxazolidine; antidepressants | DELALANDE S.A. (FR) | 1993-08-10 | — | — | US | disclosed |
| US-5196543-A | Antidepressants, tranquilizers | DELALANDE S.A. (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5171747-A | Anxiolytic agents, antidepressants | DELALANDE S.A. (FR) | 1992-12-15 | — | — | US | disclosed |
| US-5036091-A | Psychotropic drugs | DELALANDE S.A. (FR) | 1991-07-30 | — | — | US | disclosed |
| US-5036090-A | Antidepressants | DELALANDE S.A. (FR) | 1991-07-30 | — | — | US | disclosed |