Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.48 |
| ▸ | RELA | Q04206 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488160 | 1.00 | PRSS1 (0.49) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL9474452 | 0.95 | LMNA (0.52) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL9475299 | 0.95 | LMNA (0.52) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL9474446 | 0.95 | LMNA (0.52) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL9473940 | 0.93 | PRSS1 (0.48) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL9474504 | 0.92 | LMNA (0.54) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL9474515 | 0.92 | LMNA (0.54) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL9487124 | 0.90 | NPC1 (0.57) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL9473609 | 0.90 | NPC1 (0.57) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL9474954 | 0.90 | NPC1 (0.57) | PRSS1ACRLMNANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250222-A | Optically active compounds used for liquid crystalline mixtures | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |