Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 14/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491087 | 0.93 | PLA2G4A (0.35) | PLA2G4ALTB4R | |
| SCHEMBL9489923 | 0.89 | PLA2G4A (0.40) | PLA2G4ALTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL9490186 | 0.85 | PLA2G4A (0.41) | PLA2G4ALTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL9491493 | 0.85 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL9489982 | 0.84 | — | — | |
| SCHEMBL9488342 | 0.84 | PLA2G4A (0.51) | PLA2G4ALTB4R | |
| SCHEMBL9489871 | 0.82 | GLA (0.34) | PLA2G4ALTB4R | |
| SCHEMBL9490124 | 0.78 | MAPT (0.39) | — | |
| SCHEMBL9488885 | 0.77 | PLA2G4A (0.43) | PLA2G4A | |
| SCHEMBL9489950 | 0.77 | PLA2G4A (0.39) | PLA2G4ALTB4RCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337766-B1 | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICAS INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |