Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153691 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL9188668 | 0.86 | KDM4E (0.48) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL3571719 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL1061793 | 0.83 | AKR1C3 (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL1767596 | 0.83 | AKR1C3 (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL31552440 | 0.80 | AKR1C3 (0.46) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL12411070 | 0.80 | AKR1C3 (0.46) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL3934515 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL28229441 | 0.79 | KMT2A (0.49) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL19975181 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KDM4EKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1612887-A | Phosphino-aminophosphines | EASTMAN CHEM CO (US) | 2005-05-04 | — | — | CN | disclosed |
| EP-0198397-B1 | METHOD OF PRODUCING L-PHENYLALANINE | KURARAY CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| US-4743547-A | PURITY, ENZYME HYDROLYSIS | KURARAY CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |