SCHEMBL9488356

SCHEMBL9488356

O=P(O)(NCCO)OCCO

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
PPARD Q03181 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10411234 0.85 LMNA (0.30)
SCHEMBL1698794 0.78 SMN1; SMN2 (0.38)
SCHEMBL1278675 0.77 MEN1 (0.30)
SCHEMBL637890 0.74
SCHEMBL21764572 0.71 LPAR3 (0.52)
SCHEMBL21764585 0.70 LPAR3 (0.55)
SCHEMBL10884914 0.70
SCHEMBL532831 0.69 PPARD (0.39) PPARD
SCHEMBL646397 0.69
SCHEMBL26209 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315349-B1 PHOSPHOLIPASE A2 INHIBITING COMPOSITIONS AND THEIR USE YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1993-02-03 EP disclosed
US-5064817-A PHOSPHOLIPASE A2 INHIBITING COMPOSITIONS AND THEIR USE YISSUM RESEARCH DEVELOPMENT COMPANY OF HEBREW UNIVERSITY OF JERUSALEM (IL) 1991-11-12 US disclosed
EP-0315349-A1 Phospholipase A2 inhibiting compositions and their use YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1989-05-10 EP disclosed