Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | GALR2 | O43603 | 1/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | XBP1 | P17861 | 1/20 | 0.59 |
| ▸ | CCR6 | P51684 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577809 | 0.88 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL10380121 | 0.85 | ESR1 (0.58) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL15903637 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL9490047 | 0.81 | PDGFRB (0.52) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL11418690 | 0.81 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL11244929 | 0.81 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL2331208 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL27474529 | 0.79 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| Ethyl Acetate SCHEMBL6295173 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAPOLBGALR2 | |
| SCHEMBL460048 | 0.78 | CA12 (0.64) | ALDH1A1SMN1; SMN2LMNAPOLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180419-A | Herbicidal 2-(2-imidazolin-2-yl)-benzo-(5-membered)-heterocycles and the use thereof | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |