Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488674 | 1.00 | TP53 (0.59) | TP53ALDH1A1PSMB5TACR1POLB | |
| SCHEMBL23169896 | 0.90 | ALDH1A1 (0.62) | TP53ALDH1A1TACR1POLBACE | |
| SCHEMBL9487603 | 0.90 | POLB (0.67) | ALDH1A1PSMB5POLBHDAC1HDAC6 | |
| SCHEMBL9487610 | 0.90 | POLB (0.67) | ALDH1A1PSMB5POLBHDAC1HDAC6 | |
| SCHEMBL9487298 | 0.88 | TP53 (0.61) | TP53ALDH1A1PSMB5TACR1POLB | |
| SCHEMBL9487303 | 0.88 | TP53 (0.61) | TP53ALDH1A1PSMB5TACR1POLB | |
| SCHEMBL9146870 | 0.87 | TP53 (0.60) | TP53ALDH1A1TACR1POLBMMP8 | |
| SCHEMBL9385728 | 0.87 | TP53 (0.60) | TP53ALDH1A1TACR1POLBMMP8 | |
| SCHEMBL9385733 | 0.87 | TP53 (0.60) | TP53ALDH1A1TACR1POLBMMP8 | |
| SCHEMBL9146866 | 0.87 | TP53 (0.60) | TP53ALDH1A1TACR1POLBMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198397-B1 | METHOD OF PRODUCING L-PHENYLALANINE | KURARAY CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| US-4743547-A | PURITY, ENZYME HYDROLYSIS | KURARAY CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0198397-A2 | Method of producing L-phenylalanine | KURARAY CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |