SCHEMBL9488692

SCHEMBL9488692

Cc1ccc(NS(=O)(=O)NCl)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
HPGD P15428 3/20 0.53
PGR P06401 1/20 0.46
FKBP1A P62942 1/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
CDK1 P06493 1/20 0.45
CCNB1 P14635 1/20 0.45
CCNA2 P20248 1/20 0.45
CCND1 P24385 1/20 0.45
CDK2 P24941 1/20 0.45
CDK7 P50613 1/20 0.45
CCNH P51946 1/20 0.45
CCNA1 P78396 1/20 0.45
CDK6 Q00534 1/20 0.45
ALDH1A1 P00352 6/20 0.44
MAPT P10636 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10892954 0.86 CA1 (0.67) CA1CA2MEN1KMT2AHPGD
SCHEMBL15448405 0.80 CA1 (0.59) CA1CA2MEN1KMT2AHPGD
SCHEMBL9619457 0.78 CA1 (0.57) CA1CA2MEN1KMT2AHPGD
SCHEMBL3367354 0.77 CA1 (0.61) CA1CA2MEN1KMT2AHPGD
SCHEMBL23486321 0.75 ALDH1A1 (0.55) CA1CA2MEN1KMT2AHPGD
SCHEMBL10192167 0.75 CA1 (0.48) CA1CA2MEN1KMT2AHPGD
SCHEMBL82733 0.75 CA1 (0.64) CA1CA2MEN1KMT2AHPGD
SCHEMBL10191937 0.74 CA1 (0.57) CA1CA2MEN1KMT2AHPGD
SCHEMBL20963120 0.73 MEN1 (0.63) CA1CA2MEN1KMT2AHPGD
SCHEMBL11562750 0.73 CA1 (0.61) CA1CA2MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0250991-B1 METHOD FOR THE SPECIFIC DETERMINATION OF SERUM FRUCTOSAMINE CONTENT AND SUITABLE REAGENT MIXTURE Roche Diagnostics GmbH (DE) 1993-01-27 EP claimed
EP-0250991-A2 Method for the specific determination of serum fructosamine content and suitable reagent mixture Roche Diagnostics GmbH (DE) 1988-01-07 EP claimed
EP-0250991-B1 METHOD FOR THE SPECIFIC DETERMINATION OF SERUM FRUCTOSAMINE CONTENT AND SUITABLE REAGENT MIXTURE Roche Diagnostics GmbH (DE) 1993-01-27 EP disclosed
EP-0250991-A2 Method for the specific determination of serum fructosamine content and suitable reagent mixture Roche Diagnostics GmbH (DE) 1988-01-07 EP disclosed