Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA3 | P07451 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3180420 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL8954960 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL8617002 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL2138368 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL11815250 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL6917586 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL10663598 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL22615914 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL20583857 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL8943267 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122006802-A | Supported acidic catalyst, and preparation method and application thereof | 中国石油化工股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-116532146-A | Supported lanthanum paratoluenesulfonate catalyst, preparation method thereof and application thereof in methyl methacrylate synthesis reaction | 中国石油化工股份有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-112280212-B | Preparation method of flame-retardant PVC (polyvinyl chloride) flexible board | 无锡市锡山新材料科技有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-112280212-A | Preparation method of flame-retardant PVC (polyvinyl chloride) flexible board | 无锡市锡山新材料科技有限公司 | 2021-01-29 | — | — | CN | claimed |
| CN-122006802-A | Supported acidic catalyst, and preparation method and application thereof | 中国石油化工股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-122006802-A | Supported acidic catalyst, and preparation method and application thereof | 中国石油化工股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-116532146-A | Supported lanthanum paratoluenesulfonate catalyst, preparation method thereof and application thereof in methyl methacrylate synthesis reaction | 中国石油化工股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116532146-A | Supported lanthanum paratoluenesulfonate catalyst, preparation method thereof and application thereof in methyl methacrylate synthesis reaction | 中国石油化工股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116532146-A | Supported lanthanum paratoluenesulfonate catalyst, preparation method thereof and application thereof in methyl methacrylate synthesis reaction | 中国石油化工股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-115612174-A | PVC product and preparation method thereof | 青岛厚德天圆创新科技有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-115505170-A | Zinc burning inhibitor and preparation method thereof | 青岛厚德天圆创新科技有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-112280212-B | Preparation method of flame-retardant PVC (polyvinyl chloride) flexible board | 无锡市锡山新材料科技有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-112280212-A | Preparation method of flame-retardant PVC (polyvinyl chloride) flexible board | 无锡市锡山新材料科技有限公司 | 2021-01-29 | — | — | CN | disclosed |
| EP-2883865-A1 | Compound capable of binding S1P receptor and pharmaceutical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2015-06-17 | — | — | EP | disclosed |
| US-20140288034-A1 | COMPOUND CAPABLE OF BINDING S1P RECEPTOR AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-09-25 | — | — | US | disclosed |
| US-8791159-B2 | Compound capable of binding S1P receptor and pharmaceutical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-07-29 | — | — | US | disclosed |
| US-20110020324-A1 | COMPOUND CAPABLE OF BINDING S1P RECEPTOR AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD (JP) | 2011-01-27 | — | — | US | disclosed |
| US-7825109-B2 | Compound capable of binding S1P receptor and pharmaceutical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20070167425-A1 | Compound capable of binding s1p receptor and pharmaceutical use thereof | ONO PHARMACEUTICAL CO., LTD (JP) | 2007-07-19 | — | — | US | disclosed |
| EP-1661881-A2 | COMPOUND CAPABLE OF BINDING S1P RECEPTOR AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288034-A1 | COMPOUND CAPABLE OF BINDING S1P RECEPTOR AND PHARMACEUTICAL USE THEREOF | S1PR1, S1PR2, S1PR3 | GAA 4659/4885CA1 2660/4885CA2 3162/4885 |
| US-20070167425-A1 | Compound capable of binding s1p receptor and pharmaceutical use thereof | S1PR1, S1PR3, S1PR2 | GAA 4138/4885CA1 2703/4885CA2 3319/4885 |
| US-20110020324-A1 | COMPOUND CAPABLE OF BINDING S1P RECEPTOR AND PHARMACEUTICAL USE THEREOF | S1PR1, S1PR3, S1PR2 | GAA 4138/4885CA1 2703/4885CA2 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.