Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA3 | P07451 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28465424 | 0.97 | GAA (0.59) | GAACA1CA2CA12CA9 | |
| SCHEMBL8943267 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL6917586 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL8954960 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL11815250 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL10663598 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL8617002 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL22615914 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL20583857 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 | |
| SCHEMBL3180420 | 0.94 | GAA (0.62) | GAACA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554245-A | Glycosylation method with participation of trivalent iodine reagent | 华中科技大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-106978617-B | Method for electroplating metal in recessed structure | 台湾积体电路制造股份有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-108031489-B | Preparation method and application of fly ash-supported copper p-toluenesulfonate catalyst | 南京科技职业学院 | 2020-11-17 | — | — | CN | disclosed |
| CN-108031489-A | A kind of preparation method and applications of the immobilized copper p-toluene sulfonate catalysis of flyash | 南京科技职业学院 | 2018-05-15 | — | — | CN | disclosed |
| EP-1911516-B1 | HOMOGENEOUS ASYMMETRIC HYDROGENATION PROCESS | TAKASAGO PERFUMERY CO LTD (JP) | 2014-05-14 | — | — | EP | disclosed |
| EP-2392400-B1 | Homogeneous asymmetric hydrogenation method | TAKASAGO PERFUMERY CO LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-8586498-B2 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-11-19 | — | — | US | disclosed |
| CN-102675096-B | Method for preparing butyl stearate | TAICANG HUSHI REAGENT CO LTD | 2013-11-06 | — | — | CN | disclosed |
| US-8497400-B2 | Homogeneous asymmetric hydrogenation process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-30 | — | — | US | disclosed |
| US-8481791-B2 | Homogeneous asymmetric hydrogenation process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-09 | — | — | US | disclosed |
| EP-2095875-A1 | Homogeneous asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 2009-09-02 | — | — | EP | disclosed |
| US-20090203927-A1 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-1911516-A1 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST | Takasago International Corporation (JP) | 2008-04-16 | — | — | EP | disclosed |
| EP-1395547-B1 | COPPER-CATALYZED VAPOR PHASE HYDROCYANATION OF DIOLEFINIC COMPOUNDS | INVISTA TECH SARL (US) | 2005-03-16 | — | — | EP | disclosed |
| US-6753440-B2 | CATALYZING THE REACTION IN PRESENCE OF A CATALYST SUPPORTS CONTAINING COPPER (I) OR (II) FLUORINATED ALKYLSULFONATE COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-06-22 | — | — | US | disclosed |
| US-20030045740-A1 | Copper-catalyzed vapor phase hydrocyanation of diolefinic compounds | INVISTA NORTH AMERICA S.A.R.L. | 2003-03-06 | — | — | US | disclosed |
| EP-0395144-B1 | A PROCESS FOR THE PREPARATION OF AROMATIC UREAS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-06-30 | — | — | EP | disclosed |
| EP-0395144-A1 | A process for the preparation of aromatic ureas | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-10-31 | — | — | EP | disclosed |
| EP-0393789-A1 | A process for the preparation of carbamates | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-10-24 | — | — | EP | disclosed |
| US-4721819-A | Process for the preparation of higher allylic ethers | SHELL OIL COMPANY (US) | 1988-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045740-A1 | Copper-catalyzed vapor phase hydrocyanation of diolefinic compounds | AOC1, AOC2, C9 | GAA 3743/4885CA1 285/4885CA2 965/4885 |
| US-20090203927-A1 | Homogeneous asymmetric hydrogenation catalyst | HDHD5, HHAT, HACL2 | GAA 2576/4885CA1 1609/4885CA2 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.