Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599499 | 0.83 | TP53 (0.36) | TP53S1PR2S1PR1S1PR3ENPEP | |
| SCHEMBL26635231 | 0.81 | TP53 (0.44) | TP53S1PR2S1PR1S1PR3CA1 | |
| SCHEMBL28787224 | 0.80 | S1PR2 (0.33) | TP53S1PR2S1PR1S1PR3TDP1 | |
| SCHEMBL26635368 | 0.78 | TP53 (0.50) | TP53S1PR2S1PR1S1PR3CA2 | |
| SCHEMBL752524 | 0.76 | PTGS1 (0.36) | TP53S1PR2S1PR1S1PR3ENPEP | |
| SCHEMBL12900463 | 0.75 | TP53 (0.32) | TP53PTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL766602 | 0.74 | PTGS1 (0.35) | TP53S1PR2S1PR1S1PR3ENPEP | |
| SCHEMBL766601 | 0.74 | PTGS1 (0.35) | TP53S1PR2S1PR1S1PR3ENPEP | |
| SCHEMBL3411855 | 0.73 | — | — | |
| SCHEMBL13011270 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255962-B1 | OPTICALLY ACTIVE MESOMORPHIC COMPOUND | CANON KABUSHIKI KAISHA (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-5143643-A | Liquid crystals | CANON KABUSHIKI KAISHA (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0255962-A2 | Optically active mesomorphic compound | CANON KABUSHIKI KAISHA (JP) | 1988-02-17 | — | — | EP | disclosed |