SCHEMBL752524

SCHEMBL752524

CC(CCS(=O)(=O)O)OC(C)CCS(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.36
PDE4A P27815 1/20 0.36
LMNA P02545 1/20 0.36
SLC6A6 P31641 1/20 0.36
CYP2C19 P33261 1/20 0.36
BLM P54132 1/20 0.36
APP P05067 1/20 0.33
MAPK1 P28482 1/20 0.32
TP53 P04637 1/20 0.31
ENPEP Q07075 4/20 0.31
S1PR2 O95136 1/20 0.31
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL751584 0.86 APP (0.41) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL766601 0.83 PTGS1 (0.35) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL766602 0.83 PTGS1 (0.35) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL14599499 0.79 TP53 (0.36) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL16445311 0.78 PTGS1 (0.31) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL9488987 0.76 TP53 (0.34) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL329794 0.76
SCHEMBL5026578 0.74
Ammonia Solution, Strong SCHEMBL18008481 0.74 PTGS1 (0.39) PTGS1PDE4ALMNASLC6A6CYP2C19
Hydrochloric Acid SCHEMBL28099471 0.74 PTGS1 (0.39) PTGS1PDE4ALMNASLC6A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3100728-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CYDEX PHARMACEUTICALS INC (US) 2019-11-20 EP disclosed
US-10111863-B2 Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same CYDEX PHARMACEUTICALS, INC. (US) 2018-10-30 US disclosed
CN-104606681-B Include the pharmaceutical composition and its preparation and application of prasugrel and cyclodextrine derivatives 锡德克斯药物公司 2018-08-21 CN disclosed
US-9617289-B2 RSV antiviral compounds JANSSEN SCIENCES IRELAND UC (IE) 2017-04-11 US disclosed
US-20170007586-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2017-01-12 US disclosed
EP-3100728-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME Cydex Pharmaceuticals, Inc. (US) 2016-12-07 EP disclosed
US-9399067-B2 Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same CYDEX PHARMACEUTICALS, INC. (US) 2016-07-26 US disclosed
EP-2429291-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CYDEX PHARMACEUTICALS INC (US) 2016-07-06 EP disclosed
US-9240614-B2 Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES, LTD. (JP) 2016-01-19 US disclosed
US-20150259367-A1 RSV ANTIVIRAL COMPOUNDS JANSSEN SCIENCES IRELAND UC (US) 2015-09-17 US disclosed
US-20150005341-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2015-01-01 US disclosed
US-8835407-B2 Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same CYDEX PHARMACEUTICALS, INC. (US) 2014-09-16 US disclosed
EP-2579377-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES (JP) 2014-09-03 EP disclosed
EP-2579377-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2013-04-10 EP disclosed
US-20130071733-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES, LTD. (JP) 2013-03-21 US disclosed
US-20130012534-A1 Pharmaceutical Compositions Comprising Prasugrel and Cyclodextrin Derivatives and Methods of Making and Using the Same CYDEX PHARMACEUTICALS, INC. 2013-01-10 US disclosed
US-8236782-B2 Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same CYDEX PHARMACEUTICALS, INC. (US) 2012-08-07 US disclosed
EP-2429291-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CyDex Pharmaceuticals, Inc. (US) 2012-03-21 EP disclosed
WO-2010132711-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CYDEX PHARMACEUTICALS, INC. (US) 2010-11-18 WO disclosed
US-20100291056-A1 Pharmaceutical Compositions Comprising Prasugrel and Cyclodextrin Derivatives and Methods of Making and Using the Same CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2010-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170007586-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME P2RY6, GP6, PFKP PTGS1 217/4885PDE4A 47/4885LMNA 3458/4885
US-20150005341-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME P2RY6, GP6, PFKP PTGS1 217/4885PDE4A 47/4885LMNA 3458/4885
US-20130012534-A1 Pharmaceutical Compositions Comprising Prasugrel and Cyclodextrin Derivatives and Methods of Making and Using the Same P2RY6, GP6, PFKP PTGS1 217/4885PDE4A 47/4885LMNA 3458/4885
US-10111863-B2 Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same P2RY6, GP6, PFKP PTGS1 217/4885PDE4A 47/4885LMNA 3458/4885
US-20100291056-A1 Pharmaceutical Compositions Comprising Prasugrel and Cyclodextrin Derivatives and Methods of Making and Using the Same P2RY6, GP6, PFKP PTGS1 217/4885PDE4A 47/4885LMNA 3458/4885
US-20150259367-A1 RSV ANTIVIRAL COMPOUNDS ZC3HAV1, ZC3HAV1L, RTF1 PTGS1 1451/4885PDE4A 4053/4885LMNA 1504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.