Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720618 | 0.76 | ABCB1 (0.37) | KDM1AABCB1ALDH1A1HTR2AHTR2C | |
| SCHEMBL10706515 | 0.76 | ABCB1 (0.37) | KDM1AABCB1ALDH1A1HTR2AHTR2C | |
| SCHEMBL9679091 | 0.76 | ABCB1 (0.37) | KDM1AABCB1ALDH1A1HTR2AHTR2C | |
| SCHEMBL30502406 | 0.70 | ABCB1 (0.42) | KDM1AABCB1ALDH1A1CHRNA7GAA | |
| SCHEMBL29045374 | 0.70 | KDM1A (0.35) | KDM1AABCB1ALDH1A1PTGS2CHRNA7 | |
| SCHEMBL17107218 | 0.68 | KDM1A (0.41) | KDM1AABCB1ALDH1A1PTGS2HTR2A | |
| SCHEMBL8588384 | 0.67 | CHRNA7 (0.35) | KDM1ACHRNA7TSHRTRPA1CA2 | |
| SCHEMBL7398947 | 0.66 | KDM1A (0.39) | KDM1AABCB1ALDH1A1PTGS2CHRNA7 | |
| SCHEMBL24515969 | 0.65 | KDM1A (0.35) | KDM1AABCB1ALDH1A1MAPTTSHR | |
| SCHEMBL3684570 | 0.62 | KDM1A (0.40) | KDM1AABCB1ALDH1A1PTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198322-A | Positively operating radiation-sensitive mixture containing a polyfunctional α-diazo-β-keto ester and radiation-sensitive recording material containing this mixture | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-30 | — | — | US | disclosed |
| US-4996301-A | Polyfunctional α-diazo-β-keto esters and their use in light-sensitive compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |