Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 9/20 | 0.31 |
| ▸ | MAOA | P21397 | 9/20 | 0.31 |
| ▸ | MAOB | P27338 | 9/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453054 | 0.67 | RECQL (0.31) | CHRNA7 | |
| SCHEMBL365626 | 0.67 | CHRNA7 (0.32) | CHRNA7TRPA1 | |
| SCHEMBL9489237 | 0.67 | KDM1A (0.44) | CHRNA7TRPA1CA2KDM1ATSHR | |
| SCHEMBL11833918 | 0.65 | KDM1A (0.43) | KDM1AMAOAMAOBCYP2C19CYP2B6 | |
| SCHEMBL23203046 | 0.64 | CHRNA7 (0.31) | CHRNA7KDM1A | |
| SCHEMBL9100196 | 0.64 | KDM1A (0.34) | CHRNA7KDM1AMAOAMAOBHTR2C | |
| SCHEMBL10381002 | 0.62 | MAPK1 (0.37) | CHRNA7CYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL7637177 | 0.62 | KDM1A (0.50) | KDM1AMAOAMAOB | |
| SCHEMBL222998 | 0.62 | CHRNA7 (0.35) | CHRNA7TRPA1CA2KDM1AMAOA | |
| SCHEMBL6269999 | 0.62 | OPRL1 (0.34) | CA2MAOAMAOBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998046652-A1 | SUBSTITUTED POLY(PHENYLENEVINYLENE)S AND POLY(NAPTHALENEVINYLENE)S | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-10-22 | — | — | WO | disclosed |