Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 8/20 | 1.00 |
| ▸ | ITPR2 | Q14571 | 4/20 | 0.94 |
| ▸ | ITPR1 | Q14643 | 4/20 | 0.94 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.80 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.80 |
| ▸ | AKT1 | P31749 | 1/20 | 0.80 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Atrinositol SCHEMBL134177 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| Atrinositol SCHEMBL9022890 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| Atrinositol SCHEMBL636077 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| Atrinositol SCHEMBL355653 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| Atrinositol SCHEMBL888326 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| Atrinositol SCHEMBL30474862 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| Atrinositol SCHEMBL29370539 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| Atrinositol SCHEMBL180074 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| Atrinositol SCHEMBL26683544 | 0.97 | ITPR3 (0.95) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL405897 | 0.97 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPP5AINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359260-B1 | THE USE OF INOSITOLTRISPHOSPHATE FOR THE PREPARING OF A MEDICAMENT AGAINST ABNORMAL LEVELS OF LIPOPROTEINS | PERSTORP AB (SE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0359256-B1 | THE USE OF INOSITOLTRISPHOSPHATE IN THE TREATMENT OF TISSUE DAMAGE | PERSTORP AB (SE) | 1993-01-20 | — | — | EP | disclosed |
| US-5057507-A | Method of alleviating bone damage with inositoltriphosphate | PERSTORP AB (SE) | 1991-10-15 | — | — | US | disclosed |
| US-5015634-A | Wound healing agents | PERSTORP AB (SE) | 1991-05-14 | — | — | US | disclosed |
| EP-0359258-A2 | The use of inositoltrisphosphate for the preparing of a medicament against bone disorders | PERSTORP AB (SE) | 1990-03-21 | — | — | EP | disclosed |
| EP-0359260-A2 | The use of inositoltrisphosphate for the preparing of a medicament against abnormal levels of lipoproteins | PERSTORP AB (SE) | 1990-03-21 | — | — | EP | disclosed |
| EP-0359256-A2 | The use of inositoltrisphosphate in the treatment of tissue damage | PERSTORP AB (SE) | 1990-03-21 | — | — | EP | disclosed |