Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4340551 | 0.82 | KDM4E (0.63) | KDM4ETDP1NPC1L3MBTL1ADORA3 | |
| SCHEMBL1443106 | 0.82 | KDM4E (0.68) | KDM4ETDP1NPC1L3MBTL1ALDH1A1 | |
| SCHEMBL9488463 | 0.79 | KDM4E (0.50) | KDM4ETDP1MAPK14TGFBR1NPC1 | |
| SCHEMBL1780998 | 0.78 | KDM4E (0.56) | KDM4ETDP1TGFBR1NPC1L3MBTL1 | |
| SCHEMBL5026240 | 0.74 | KDM4E (0.58) | KDM4ETDP1MAPK14NPC1L3MBTL1 | |
| SCHEMBL19690959 | 0.74 | KDM4E (0.58) | KDM4ETDP1L3MBTL1ALOX15GRM5 | |
| SCHEMBL10157013 | 0.74 | KDM4E (0.57) | KDM4ETDP1NPC1L3MBTL1RAB9A | |
| SCHEMBL20665292 | 0.74 | KRAS (0.42) | KDM4ETDP1MAPK14TGFBR1NPC1 | |
| SCHEMBL5479409 | 0.74 | CYP1A2 (0.64) | KDM4ETDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4339744 | 0.73 | CCR1 (0.56) | KDM4ETDP1NPC1L3MBTL1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250533-A | Fungicidal pyridinylpyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-05 | — | — | US | claimed |